Immunoglobulin G4-Related Disease Masquerading Anaplastic Thyroid Carcinoma

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Immunoglobulin G4-related disease masquerading as tonsil carcinoma.

An 85-year-old man presented with a history of odynophagia since March 2015. He was a chronic smoker but did not drink alcohol. He had a medical history of hypertension, diabetes mellitus, and gout. He was first seen by us in April 2015. At the first presentation, physical examination revealed an irregular 3-cm ulcerative mass arising from the left tonsil (Fig 1). The rest of his oral cavity wa...

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Immunoglobulin G4-Related Thyroid Diseases.

Immunoglobulin G4-related disease (IgG4-RD) is a new disease category involving many organ systems, including the endocrine system in general and the thyroid in particular. Since an initial association was made between hypothyroidism and autoimmune (IgG4-related) pancreatitis, more forms of IgG4-related thyroid disease (IgG4-RTD) have been recognized. Four subcategories of IgG4-RTD have so far ...

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Esophageal Involvement of Immunoglobulin G4-Related Disease

Immunoglobulin G4 (IgG4)-related disease is characterized by the typical histopathological features of a dense lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells, a high ratio of IgG4- to IgG-positive cells, storiform fibrosis (cellular fibrosis organized in an irregular whorled pattern), obliterative phlebitis, and variable presence of eosinophils. The disease exhibits systemic in...

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Nasal manifestations of immunoglobulin G4-related disease.

OBJECTIVES/HYPOTHESIS Immunoglobulin (Ig)G4-related disease is a systemic syndrome, characterized by sclerosing lesions that mainly affect the exocrine tissue. Although some patients with IgG4-related disease complain of nasal symptoms, there are few reports concerning the nasal manifestations of this disease. We investigated the clinical and pathological features of the nasal manifestations of...

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Riedel's thyroiditis masquerading as anaplastic thyroid carcinoma: a case report

INTRODUCTION Riedel's thyroiditis is a rare thyroid disease characterized by dense fibrous tissues that replace the thyroid gland and invade the adjacent structures that can mimic thyroid malignancy. We discuss the presentation, investigation and management of this very rare condition. CASE PRESENTATION We present a case of a 59-year-old African-Caribbean man who presented with a rapidly grow...

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ژورنال

عنوان ژورنال: Journal of Clinical Otolaryngology Head and Neck Surgery

سال: 2018

ISSN: 1225-0244,2713-833X

DOI: 10.35420/jcohns.2018.29.2.301